Secondary glomerular disease

Levy, Jeremy

doi:10.1016/j.mpmed.2007.06.008

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Volume 35, Issue 9 , Pages 497-499, September 2007

Secondary glomerular disease

Jeremy Levy PhD FRCP is a Consultant Nephrologist at the West London Renal and Transplant Centre, Hammersmith Hopsital, London, UK. He trained in Cambridge, London and Oxford. He also organizes renal teaching for Imperial College London, is Training Director for Renal SpR training in North Thames, and is Director of Education for the Hammersmith Hospitals Trust. His major clinical interests are in immune-mediated renal disease (especially vasculitis and systemic lupus erythematosus), chronic kidney disease, acute kidney injury, and haemodialysis. Competing interests: none declared

Abstract

Secondary glomerular diseases are common worldwide and can manifest in many ways. Bacterial and viral infections, especially hepatitis and HIV, can cause a variety of patterns of glomerular injury often presenting with nephrotic syndrome, as can tumours and drugs. Diabetes and systemic lupus erythematosus are also important causes. Identifying underlying agents leads to specific treatments and can lead to resolution of the glomerular injury. In this review we explore the commonest secondary glomerular diseases and their management.

Keywords: focal segmental glomerulosclerosis, glomerulonephritis, membranous, mesangiocapillary nephritis