Medicine
Volume 35, Issue 9 , Pages 483-488, September 2007

Medical management of renal transplantation

Paul Sweny MD FRCP is a Consultant Nephrologist at the Royal Free Hospital, London, UK. Competing interests: none declared

Abstract 

Renal transplantation is the preferred treatment for all patients (if suitable) with end-stage renal failure, and offers a significant survival advantage over dialysis. Complications derive mainly from the imperfect immunosuppressive regimen available to prevent rejection. Additional complications occur to patients with poorly functioning grafts as these patients have the added burden of a reduced glomerular filtration rate. The major issues for medical management following transplantation are cardiovascular disease, infection and cancer.

Keywords: immunosuppression, opportunistic infections, renal transplantation, viral-induced cancers

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PII: S1357-3039(07)00183-1

doi:10.1016/j.mpmed.2007.06.011

Medicine
Volume 35, Issue 9 , Pages 483-488, September 2007