Medicine
Volume 35, Issue 12 , Page 626, December 2007

Isopropanol

Allister Vale MD FRCP FRCPE FRCPG FFOM FAACT FBTS is Director of the National Poisons Information Service (Birmingham Unit) and the West Midlands Poisons Unit at City Hospital, Birmingham, UK. Competing interests: none declared

Abstract 

Isopropanol is oxidized to acetone by hepatic alcohol dehydrogenase. The effects of isopropanol on the nervous system are similar to those of ethanol, but are probably more severe. Coma and respiratory depression are the major sequelae following substantial exposure. The mainstay of treatment is supportive care, though in severe cases haemodialysis will remove isopropanol and acetone effectively.

Keywords: acetone, haemodialysis, isopropanol

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PII: S1357-3039(07)00313-1

doi:10.1016/j.mpmed.2007.09.002

Medicine
Volume 35, Issue 12 , Page 626, December 2007

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