Medicine
Volume 36, Issue 6 , Pages 295-299, June 2008

Opportunistic fungal lung infections

Simon Goldenberg MSc PGDipID is a Specialist Registrar in Medical Microbiology at St Thomas' Hospital, London, UK. Competing interests: none declared

Nicholas Price BSc FRCP PhD DTM&H is Lead Clinician and Consultant in Infectious Diseases at St Thomas’ Hospital, London, UK. Competing interests: none declared

Abstract 

Fungi are ubiquitous in the environment. Differentiating between invasive disease and harmless colonization is frequently difficult, but almost all endemic fungi causing significant lung disease occur in immunocompromised hosts. The particular fungal species involved, and the clinical manifestations that result, are dictated by the nature and degree of the immunocompromised state. Some non-endemic fungi cause significant disease in the immunocompetent host or reactivate in patients that become immunocompromised after many years of asymptomatic latent infection.

Keywords: aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, cryptococcosis, fungal lung infections, histoplasmosis, paracoccidioidomycosis, pneumocystis, zygomycosis

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PII: S1357-3039(08)00103-5

doi:10.1016/j.mpmed.2008.03.010

Medicine
Volume 36, Issue 6 , Pages 295-299, June 2008