Skin manifestations of systemic disease

Abstract 

This article gives an overview of the common cutaneous manifestations which may present to the acute physician and give a pointer to an underlying general medical condition. Topics covered include autoimmune conditions such as lupus erythematosus, dermatomysositis and scleroderma, endocrine conditions such as diabetes and thyroid disease, general medical conditions such as sarcoid, pyoderma gangrenosum, and cutaneous signs of internal malignancy and flushing.

Keywords: acanthosis nigricans, cutaneous lupus, dermatomyositis, erythema nodosum, flushing, genodermatosis, morphoea, necrobiosis lipoidica, paraneoplastic dermatoses, pretibial myxoedema, pyoderma gangrenosum, sarcoidosis