Medicine
Volume 37, Issue 11 , Pages 567-573, November 2009

Bacterial meningitis and brain abscess

K Ananth Ramakrishnan MBBS MRCPCH is a Specialist Registrar in Paediatric Intensive Care at the Southampton University Hospitals NHS Trust, United Kingdom. Competing interests: none declared

Michael Levin PhD FRCP is a Professor of Paediatrics and International Child Health at Imperial College London, UK. Competing interests: none declared

Saul N Faust MRCPH PhD FHEA is a Senior Lecturer in Paediatric Immunology and Infectious Diseases at the University of Southampton, UK. Competing interests: none declared

Abstract 

Bacterial meningitis and brain abscess continue to cause significant morbidity and mortality in children and adults. This article reviews recent changes in the epidemiology caused by new immunisations; the clinical manifestations at different ages; advances in the understanding of the pathophysiology; and current treatment strategies including the use of adjunctive therapies such as corticosteroids.

Keywords: adults, bacterial, brain abscess, children, diagnosis, meningitis, pathophysiology, prevention, treatment

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PII: S1357-3039(09)00240-0

doi:10.1016/j.mpmed.2009.08.010

Medicine
Volume 37, Issue 11 , Pages 567-573, November 2009

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